Scientists from Japan, studying the effect of fatty acids on the human body, have established a relationship between the intake of these substances in the bloodstream of a pregnant woman and the development of the brain of the future child. The results of the work are published in the publication "Stem Cells".
Omega-3 and Omega-6 are not synthesized in the body of mammals and come only with food. Carrying out important functions (oxygen delivery to tissue, protection of cell membranes and energy deposition), acids are irreplaceable.
The source of Omega-6 acids is vegetable oils. Omega-3 acids are mainly found in marine fish, whose presence in the diet is important for normal course of pregnancy, reducing the level of pedestrian depression and development of the child's brain in the first year life.
To learn how the lack of Omega-3 and the imbalance of fatty acids affect the body, a group of scientists from Japan, led by Professor Noriko Osumi (Noriko Osumi) conducted an experiment in which pregnant laboratory female rodents received food with a predominant content of Omega-6, but a low level Omega-3. This changed ratio of fatty acids is common for people. For the purity of the experiment, the second group of pregnant females was fed a balanced diet.
The researchers found that the brain of the rat, whose mothers received mostly Omega-6, is much smaller than the brain of those calves whose mothers were balanced. The pups from the experimental group had certain deviations in emotional behavior. So, despite the fact that after the birth of rodents were given proper nutrition, they were diagnosed with anxiety at a more mature age.
After studying the metabolism of the developing brain of rodents, scientists were able to say that metabolites of omega acids are an important foundation for the growth of stem cells.
Rats, who during pregnancy mostly received omega-6, stem cells had more a high rate of development, which increased the production of omega-6 oxide, which stimulates early aging neurons.
The authors of the scientific work consider that the obtained results clearly demonstrate that the excess of Omega-6 acids in the absence of Omega-3 causes abnormal development of the brain.